The former world champion, who won belts in five divisions, was last in action this summer when he fought Logan Paul. There was no winner as part of the event rules, but he was clearly the more accomplished fighter against the YouTuber.
Mayweather, now 44, last fought professionally when he took his record to 50-0 with a victory over UFC fighter Conor McGregor.
In December 2018 on New Year’s Eve he fought another exhibition in Tokyo, against kickboxer Tenshin Nasukawa, winning in the first round after three early knockdowns.
The now-retired fighter hinted that he would be back in an exhibition event, but was not clear if that included plans for him to return to the ring.
Mayweather said on his IG account: “We got a lot going on. 2022. Events, exhibitions, and big business. We can’t be stopped. The Money team. Be on the lookout, right here, in Dubai.”